Description: The hormonal mechanisms underlying appetite, maintenance of energy balance, and body weight are paramount. The critical hormones in this regulatory cycle are leptin, ghrelin, insulin, and peptide YY. Hence, such hormones orchestrate a food-ingested response to control hunger responses and satiety. The experts will present new insights on recent research about the latest updates on hormonal controls of appetite, its role in treating obesity, and metabolic diseases at DEWC. Whereas leptin signals satiety, ghrelin acts as an appetite stimulant; insulin, on the other hand, has been shown to regulate glucose and, consequently, appetite. Disturbances in these pathways of hormones can lead to overeating and subsequent weight gain, furthering obesity and metabolic disorders. Elucidation of these mechanisms is a gift of targeted therapies for appetite regulation and weight management.