Cardiac and cardiometabolic diseases remain one of the leading causes of health problems and deaths worldwide, generating growing concern about risk factors and the adoption of a healthier lifestyle. Allulose, a low-calorie sugar with a taste similar to common sugar, emerges as a promising alternative. Unlike traditional sugar, allulose does not cause glycemic spikes, making it an interesting option for individuals with diabetes, insulin resistance, or other metabolic disorders. This work aims to provide an overview of the importance of cardiovascular health, highlighting risk factors and the need for dietary changes, focusing on the potential of allulose as a sugar substitute. Articles were reviewed in the MEDLINE, EMBASE, PubMed, Scopus, and Web of Science databases, using terms such as "Allulose", "D-psicose", "Diabetes Mellitus", "Glycemic control", and "metabolic changes". Out of 19 identified articles, 9 were selected for analysis. The results reinforce the importance of awareness about risk factors and aging, in addition to highlighting allulose as an effective strategy in the prevention of cardiometabolic diseases, contributing to more efficient metabolic control.